Crospovidone (PVPP)

Crospovidone (PVPP)

This product is a water-insoluble homopolymer synthesized from n-ethylene-2-pyrrolidone.

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Data Sheet

General Information
Product Name Crospovidone（PVPP）
HS Code 39059900
CAS Number 9003-39-8
Standard CP、USP、EP、BP
Packing Specification 20kg/ drum
Storage Condition Room temperature, Sealed
Product Character This product is white or white powder, almost odorless, moisture-inducing, insoluble in water, ethanol, trichloromethane or ether.
Physicochemical Property
Density 1.144g/cm3
Molecular Formula (C6H9NO)n
Refractive Index N/A
Boiling Point 217.6℃ at 760 mmHg
Vapor Pressure N/A
Molecular Weight 111.1418(monomer)
Fusing Point 130℃
Flash Point 93.9℃

Features

  •   Crospovidone has strong swelling properties and complex ability with many kinds of substances, and is widely used in the pharmaceutical industry as a disintegrator of tablets, a dissolution accelerator of insoluble drugs, a suspension stabilizer of mixtures, etc.
  •   Crospovidone is a water-insoluble tablet disintegrator used in direct tablet pressing and dry or wet pellet pressing processes with a concentration of 2% to 5%.
  •   Crospovidone is an excellent water-clear polymer used in oral liquids and local suspensions, ready-to-use suspensions, dry syrups, instant drink granules, and improves the release of active substances in tablets, capsules, and granules.
  •   Crospovidone and active drug test will give you a mixture to improve the dissolution and bioavailability of the drug, is an effective dissolution promoter.
  •   Crospovidone and polyphenol can form stable complexes, which can be used to refine water-soluble or alcohol-containing herbal extracts and tinctures, and improve the stabilizer of plant medicine.
  •   Crospovidone hydrogel can be used as a static cell culture substrate, its insolubility makes it unable to penetrate the cell membrane, while its good water absorption and physiological inertia can protect and promote cell growth.
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