Sodium Starch Glycolate (SSG)

Sodium Starch Glycolate (SSG)

The starch derivatives of this strain are mainly used as disintegrators in solid preparations. It has good water absorption and expansion, while accelerating the disintegration of the tablet with compressibility, can improve the formability of the tablet, increase the hardness of the tablet without affecting its disintegration, the dosage is 0.5-8%, the usual dosage is 3%. The method of use is generally external or external addition. It also has more powerful swelling properties, which can accelerate the disintegration of tablets, thereby improving the dissolution and bioavailability of drugs. Generally, the usual dosage is 2-8%, which can be used for external or internal and external addition.

Data Sheet

General Information
Product Name Sodium Starch Glycolate(SSG)
HS Code 35051000
CAS Number 9063-38-1
Standard CP、USP、BP、EP
Packing Specification 25kg/ drum、25kg/ bag
Storage Condition Room temperature, Sealed
Product Character This product is white or white powder, odorless, moisture-inducing. Disperses into a viscous colloidal solution in water, insoluble in ethanol or ether.
Physicochemical Property
Density N/A
Molecular Formula O(C8H10O7Na)n
Refractive Index N/A
Boiling Point N/A
Vapor Pressure N/A
Molecular Weight 50000~100000
Fusing Point N/A
Flash Point N/A

Features

  •   Sodium Starch Glycolate can achieve rapid and significant swelling through rapid water absorption, thus playing the role of disintegration.
  •   Suitable for direct pressing or wet granulation process. The range commonly used in formulations is 2 to 8%. Sodium Starch Glycolate has also been studied as a suspension aid.
  •   Although the disintegration of many disintegrants is affected by hydrophobic excipients (such as lubricants), Sodium Starch Glycolate is less affected by it. Increasing tablet pressure also seems to have no effect on disintegration time.
  •   The tablets prepared with Sodium Starch Glycolate have good Storage Condition properties. Although Sodium Starch Glycolate has a very strong hygroscopic property, it has good stability. Should be stored in a closed container, so as not to be affected by humidity, temperature changes, resulting in caking.
  •   Stored at the right temperature and humidity, its physical properties can be maintained for up to 3 years.
  •   It has incompatibility with ascorbic acid and aminoglycoside antibiotics.
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